Postdoctoral Research Associate Yeqi joined the Lin lab in 2021 as a postdoctoral associate. He received a Ph.D degree from the Nanjing Normal University. His previous work mainly focuses on the drug resistance in Aspergillus fumigatus. Now his project involves in how the cryptococcus promotes host protective immune response. He is exploring which antigens presented in the cryptococcal cells and how to use these antigens or filamentous strains as vaccine candidates. With these works, he hopes to unravel the molecular mechanisms of antigens providing the protective effect. Research Labs (via personnel): Xiaorong Lin Labs: Lin Lab Selected Publications Selected Publications: 1. Li Y, Ambati S, Meagher BR, and Lin X. Developing mRNA lipid nanoparticle vaccine for cryptococcosis. NPJ Vaccines. 2025 Feb 04; 10(1):24. 2. Li Y, Pham T, Hipsher K, Lee C, Jiao J, Penninger MJ, Kronstad WJ, Fan Y, Zhao Y, Ambati S, Meagher BR, Xie X, and Lin X. Identification of a protective antigen reveals the trade-off between iron acquisition and antigen exposure in a global fungal pathogen. Proc Natl Acad Sci U S A. 2025 Feb 13; 122 (7) e2420898122. 3. Li Y, Chadwick B, Pham T, Xie X, Lin X. Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans. mBio 2024 May 14:e0092024. 4. Pham T#, Li Y#, Watford W, Lin X. Vaccination with a ZNF2oe strain provides long-lasting protection against cryptococcosis and is effective in immunocompromised hosts. Infect Immun 2023 Jul 18;91(7):e0019823.. 5. Li Y, Pham T, Xie X, Lin X. Identification and characterization of an intergenic “safe haven” region in human fungal pathogen Cryptococcus gattii. J. Fungi 2022, 8, 178.
